Gene information
Official symbol VKORC1
Official full name vitamin K epoxide reductase complex subunit 1
Gene type protein-coding gene
Chromosome16p11.2
Previous symbolVKCFD2
Resources
Entrez Gene 79001
HGNC HGNC:23663
Ensembl ENSG00000167397
Vega OTTHUMG00000047408
UCSC uc002eas.4
GO terms: 8 records
GO Description Category LogP Number of genes Detail
GO:0001501 skeletal system development GO Biological Processes -17.2073293 69 More
GO:0006766 vitamin metabolic process GO Biological Processes -3.00017540 12 More
GO:0006775 fat-soluble vitamin metabolic process GO Biological Processes -3.82142288 8 More
GO:0006805 xenobiotic metabolic process GO Biological Processes -8.19045514 12 More
GO:0009410 response to xenobiotic stimulus GO Biological Processes -32.6021211 82 More
GO:0016491 oxidoreductase activity GO Molecular Functions -14.1519969 39 More
GO:0060348 bone development GO Biological Processes -12.2474877 36 More
GO:0071466 cellular response to xenobiotic stimulus GO Biological Processes -9.33788411 28 More
Drug-Gene interaction
view
Related drugs: 10 records
Drug name Interaction type Source PMID View
acenocoumarol inhibitor TdgClinicalTrialTENDPharmGKBTTD 229203942644513825042728192254511901871923602689187818522447449816611310275812002726282417596133255198261987589219277427274881762495625218574025295772573098353629479633273351282576935725089947211480492677761025244877286891792365102325001883189504641927026324919870241081932257135618698879117523521869034223774101255213562163659822592842224861822943289723423913231596392803324516815313237749412002028323473641157907821686982119515014 view
dicumarol inhibitor TdgClinicalTrialChemblInteractionsTENDTTD 1175235224241181713928417016423 view
fluindione PharmGKB 21883387 view
menadione cofactor TdgClinicalTrialTEND 17139284161020541701642316677080 view
phenindione inhibitor TdgClinicalTrialChemblInteractionsTENDTTD 1175235217139284946584317016423 view
phenprocoumon inhibitor TdgClinicalTrialChemblInteractionsTENDPharmGKBTTD 22920394264451381922545118629445236026892083398016201835187818522447449827581200272628241759613317192772255198262037662927488176269849781857402529577257309835362576935721057703320798621148049267776102524487728689179250018831895046419270263249198702257135627060101869887911752352186903422377410125521356216365982259284223299853294328972342391328033245168153132002028324224579 view
tecarfarin TdgClinicalTrialTTD view
warfarin inhibitor TdgClinicalTrialTENDPharmGKBTTDFDA 2007212421174619213263132644513814765195187523792163514724029542250427282360268916815312282623452083398017110455225348261712410117042764213837712252832629781049244744981535862325594941166113102758120027262824250264562838249821318593170150521614179418466099255198262531278919875892165808981798911016432637316539731913523116888441274881762190089119387626222482861718921822349464968479817456829169834001974556317391071262572493139595820203262174137692118575218574025228545392957725720615525262191581703172026433837247283852299033128429387226166552306174616270629257693571824090423183958175103082198179720339978198744741803030715888487262239451958244015938684170495862041087715883587211480491711119926777610252448772868917917653141172753172042112625001883169601441594709016821005173299852508420518950464119268931293113420833655293967382491987022075505191770292058583419794411225713561929721918698879117523521689057818690342237741012267619223159229220100992712189925521356168474292259284224019055232083221467682114765194231042592394943119077919280493621649347925989350290547602943289723423913243300002117672116611750280332452038635917112295158655941790697216815313159304191667606821273734292989952204043915790782111278542254950217161452182344032111019215597574232796432393203718542936 view
warfarin potassium inhibitor ChemblInteractions view
warfarin sodium inhibitor ChemblInteractions view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_024006.6:c.*134G>A genomics warfarin[treatment (pharmacotherapy)] acute myocardial infarction Kringen MK et al. J Biomed Biotechnol. 2011
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